Infusion intravenous (IV) ketamine stands out as a superior option compared to Spravato (esketamine nasal spray) in several key aspects of depression treatment. Firstly, infusion ketamine offers precise control over dosage and infusion rate, allowing for tailored treatment plans that can be adjusted according to individual response and tolerance.

This flexibility ensures optimal therapeutic outcomes, particularly for individuals with severe or treatment-resistant depression who may require higher doses or longer treatment durations. Additionally, the longer duration of infusion sessions allows for a more profound and enduring antidepressant effect, leading to sustained relief of depressive symptoms over time.

intravenous (IV) ketamine stands out as a superior option compared to Spravato (esketamine nasal spray).

Ketamine Infusion Therapy involves administering racemic ketamine intravenously under medical supervision. Ketamine, an NMDA receptor antagonist, has been shown to produce rapid antidepressant effects, often within hours. The treatment typically involves multiple sessions, with the frequency and duration tailored to the individual's needs.

Spravato (Esketamine) is a nasal spray approved by the FDA for treatment-resistant depression. It contains esketamine, the S-enantiomer of ketamine, which is also an NMDA receptor antagonist. Spravato is used in conjunction with an oral antidepressant and is administered in a clinical setting due to its potential for side effects and misuse.

Temporary or Permanent?

Additionally, while Spravato may offer rapid relief and a temporary alleviation of depressive symptoms, infusion IV ketamine holds the potential for more profound and enduring healing. While Spravato's effects may wear off between doses, infusion ketamine's longer duration and potential for synaptic repair and neuroplasticity suggest the possibility of lasting changes in brain function, leading to sustained remission of depression. By targeting the underlying neurobiological mechanisms of depression, infusion ketamine addresses the root causes of the condition, potentially offering a pathway to lasting recovery and improved mental well-being. Thus, while both treatments provide relief, infusion ketamine's focus on long-term healing distinguishes it as a superior option for individuals seeking comprehensive and enduring relief from depression.

SAFE USE

Spravato rapidly relieves symptoms of depression and anxiety without changing the underlying behaviors that are causing the symptoms, consequently symptoms worsen to overcome the spravato. Safe use requires extreme monitoring with exacting tolerances. Complete Ketamine has specific protcol to repair the damage from improper use. Patients transfer to Complete Ketamine as a result of worsening symptoms.

Conclusion

While both ketamine infusion and Spravato offer new hope for individuals with treatment-resistant depression, ketamine infusion therapy may present several advantages. Its rapid onset, customizable dosing, and controlled administration can provide more immediate and personalized relief for many patients. However, it's essential for individuals to consult with their healthcare providers to determine the most appropriate treatment based on their specific needs and medical history.